AI Round-up: Karpathy Reactions, OpenAI’s Dealmaking, & Bubble Reality Check

This episode features Rob Toews from Radical Ventures and Ari Morcos, Head of Research at Datology AI, reacting to Andrej Karpathy's recent statement that AGI is at least a decade away and that current AI capabilities are "slop." The discussion explores whether we're in an AI bubble, with both guests pushing back on overly bearish narratives while acknowledging legitimate concerns about hype and excessive CapEx spending. They debate the sustainability of AI scaling, examining whether continued progress will come from massive compute increases or from efficiency gains through better data quality, architectural innovations, and post-training techniques like reinforcement learning. The conversation also tackles which companies truly need frontier models versus those that can succeed with slightly-behind-the-curve alternatives, the surprisingly static landscape of AI application categories (coding, healthcare, and legal remain dominant), and emerging opportunities from brain-computer interfaces to more efficient scaling methods.

0:00 Intro
1:04 Debating the AI Bubble
1:50 Over-Hyping AI: Realities and Misconceptions
3:21 Enterprise AI and Data Center Investments
7:46 Consumer Adoption and Monetization Challenges
8:55 AI in Browsers and the Future of Internet Use
14:37 Deepfakes and Ethical Concerns
26:29 AI's Impact on Job Markets and Training
31:38 Google and Anthropic: Strategic Partnerships
34:51 OpenAI's Strategic Deals and Future Prospects
37:12 The Evolution of Vibe Coding
44:35 AI Outside of San Francisco
48:09 Data Moats in AI Startups
50:38 Comparing AI to the Human Brain
56:07 The Role of Physical Infrastructure in AI
56:55 The Potential of Chinese AI Models
1:03:15 Apple's AI Strategy
1:12:35 The Future of AI Applications

With your co-hosts: 
@jacobeffron 
- Partner at Redpoint, Former PM Flatiron Health 
@patrickachase 
- Partner at Redpoint, Former ML Engineer LinkedIn 
@ericabrescia 
- Former COO Github, Founder Bitnami (acq’d by VMWare) 
@jordan_segall 
- Partner at Redpoint